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KMID : 0903519980410040261
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
1998 Volume.41 No. 4 p.261 ~ p.264
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Synthesis and Configuration Determination of Styrylquinolines as Leukotriene D4 Antagonist Precursors
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Lim, Yoong Ho
Koh, Dong Soo/Koo, Bon Jeong/Yong, Yeon Joong
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Abstract
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Differently substituted styrylquinoline derivatives (6-9) were synthesized by condensation of quinaldine (1) and corresponding substituted benzaldehydes (2-5). Their relative configuration at C11-C12 and coupling patterns were determined by NMR techniques.
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